KSP inhibitor SB743921 induces death of multiple myeloma cells via inhibition of the NF-κB signaling pathway

SB743921 is a potent inhibitor of the spindle protein kinesin and is being investigated in ongoing clinical trials for the treatment of myeloma. However, little is known about the molecular events underlying the induction of cell death in multiple myeloma (MM) by SB743921, alone or in combination tr...

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Bibliografiske detaljer
Udgivet i:BMB Rep
Main Authors: Song, In-Sung, Jeong, Yu Jeong, Nyamaa, Bayalagmaa, Jeong, Seung Hun, Kim, Hyoung Kyu, Kim, Nari, Ko, Kyung Soo, Rhee, Byoung Doo, Han, Jin
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Biochemistry and Molecular Biology 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911184/
https://ncbi.nlm.nih.gov/pubmed/25772758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2015.48.10.015
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