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Molecular Dynamics Simulations and Structural Analysis to Decipher Functional Impact of a Twenty Residue Insert in the Ternary Complex of Mus musculus TdT Isoform

Insertions/deletions are common evolutionary tools employed to alter the structural and functional repertoire of protein domains. An insert situated proximal to the active site or ligand binding site frequently impacts protein function; however, the effect of distal indels on protein activity and/or...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Mutt, Eshita, Sowdhamini, Ramanathan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911049/
https://ncbi.nlm.nih.gov/pubmed/27311013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157286
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