Time to Definitive Health-Related Quality of Life Score Deterioration in Patients with Resectable Metastatic Colorectal Cancer Treated with FOLFOX4 versus Sequential Dose-Dense FOLFOX7 followed by FOLFIRI: The MIROX Randomized Phase III Trial

PURPOSE: We previously showed that a sequential chemotherapy with dose-dense oxaliplatin (FOLFOX7) and irinotecan (FOLFIRI; irinotecan plus 5-fluorouracil/leucovorin) is not superior to FOLFOX4 in patients at advanced stage of colorectal cancer with liver metastases. Here we aimed to determine wheth...

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Udgivet i:PLoS One
Main Authors: Hamidou, Zeinab, Chibaudel, Benoist, Hebbar, Mohamed, Hug de Larauze, Marine, André, Thierry, Louvet, Christophe, Brusquant, David, Garcia-Larnicol, Marie-Line, de Gramont, Aimery, Bonnetain, Franck
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910973/
https://ncbi.nlm.nih.gov/pubmed/27310205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157067
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