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Metformin inhibits prostate cancer cell proliferation, migration, and tumor growth through upregulation of PEDF expression

Metformin has been reported to inhibit the growth of various types of cancers, including prostate cancer. Yet the mode of anti-cancer action of metformin and the underlying mechanisms remain not fully elucidated. We hypothesized that the antitumorigenic effects of metformin are mediated through upre...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Chen, Xiaowan, Li, Chenli, He, Tiantian, Mao, Jiating, Li, Chunmei, Lyu, Jianxin, Meng, Qing H.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910909/
https://ncbi.nlm.nih.gov/pubmed/26987032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1156273
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