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Safety concerns over the use of intestinal permeation enhancers: A mini-review
Intestinal permeation enhancers (PEs) are key components in ∼12 oral peptide formulations in clinical trials for a range of molecules, primarily insulin and glucagon-like-peptide 1 (GLP-1) analogs. The main PEs comprise medium chain fatty acid-based systems (sodium caprate, sodium caprylate, and N-[...
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Publicado no: | Tissue Barriers |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4910835/ https://ncbi.nlm.nih.gov/pubmed/27358756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21688370.2016.1176822 |
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