Unlocking tumor vascular barriers with CXCR3: Implications for cancer immunotherapy

Promising cancer immunotherapeutics depend on mobilization of cytotoxic T cells across tumor vascular barriers through mechanisms that are poorly understood. Recently, we discovered that the CXCR3 chemokine receptor uniquely functions as the master-regulator of cytotoxic CD8(+) T cell extravasation...

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Pubblicato in:Oncoimmunology
Autori principali: Mikucki, Maryann E., Skitzki, Joseph J., Frelinger, John G., Odunsi, Kunle, Gajewski, Thomas F., Luster, Andrew D., Evans, Sharon S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910745/
https://ncbi.nlm.nih.gov/pubmed/27467928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1116675
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