STAT3 inhibition for cancer therapy: Cell-autonomous effects only?

A paper recently published in Science Translational Medicine describes a next-generation antisense oligonucleotide that specifically downregulates the expression of human signal transducer and activator of transcription 3 (STAT3). Such an oligonucleotide, AZD9150, exerts antineoplastic effects on a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncoimmunology
Main Authors: Kroemer, Guido, Galluzzi, Lorenzo, Zitvogel, Laurence
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Editorial
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910743/
https://ncbi.nlm.nih.gov/pubmed/27467938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1126063
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