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Clinical activity and safety of Pembrolizumab in Ipilimumab pre-treated patients with uveal melanoma

Background: Untreated metastatic uveal melanoma (UM) carries a grave prognosis. Unlike cutaneous melanoma (CM), there are no established treatments known to significantly improve outcomes for a meaningful proportion of patients. Inhibition of the PD1–PDL1 axis has shown promise in the management of...

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Bibliografske podrobnosti
izdano v:Oncoimmunology
Main Authors: Karydis, Ioannis, Chan, Pui Ying, Wheater, Matthew, Arriola, Edurne, Szlosarek, Peter W., Ottensmeier, Christian H.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910726/
https://ncbi.nlm.nih.gov/pubmed/27467964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1143997
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