Ovarian cancer chemokines may not be a significant barrier during whole tumor antigen dendritic-cell vaccine and adoptive T-cell immunotherapy

Tumor barriers preventing T-cell homing and engraftment should be neutralized during cancer immunotherapy. We recently discovered that ovarian cancer expresses quasi-universal chemokines that can support T-cell homing. Furthermore, T cells elicited by whole tumor antigen dendritic-cell vaccines expr...

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Publicado en:Oncoimmunology
Autores principales: Zsiros, Emese, Dangaj, Denarda, June, Carl H., Kandalaft, Lana E., Coukos, George
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910715/
https://ncbi.nlm.nih.gov/pubmed/27467909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1062210
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