TERT Core Promotor Mutations in Early-Onset Bladder Cancer

Activating mutations in the core promoter of the TERT gene have been described in many different tumor entities. In vitro models showed a two- to fourfold increase in transcriptional activity of the TERT promoter through creation of a consensus binding motif for Ets/TCF transcription factors caused...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Giedl, Johannes, Rogler, Anja, Wild, Andreas, Riener, Marc-Oliver, Filbeck, Thomas, Burger, Maximilian, Rümmele, Petra, Hurst, Carolyn, Knowles, Margaret, Hartmann, Arndt, Zinnall, Ulrike, Stoehr, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910583/
https://ncbi.nlm.nih.gov/pubmed/27313781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.15006
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