The Mineralocorticoid Agonist Fludrocortisone Promotes Survival and Proliferation of Adult Hippocampal Progenitors

Glucocorticoid receptor (GR) activation has been shown to reduce adult hippocampal progenitor cell proliferation and neurogenesis. By contrast, mineralocorticoid receptor (MR) signaling is associated with neuronal survival in the dentate gyrus of the hippocampus, and impairment of hippocampal MR has...

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Bibliographische Detailangaben
Veröffentlicht in:Front Endocrinol (Lausanne)
Hauptverfasser: Gesmundo, Iacopo, Villanova, Tania, Gargantini, Eleonora, Arvat, Emanuela, Ghigo, Ezio, Granata, Riccarda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910464/
https://ncbi.nlm.nih.gov/pubmed/27379018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00066
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