The Mineralocorticoid Agonist Fludrocortisone Promotes Survival and Proliferation of Adult Hippocampal Progenitors

Glucocorticoid receptor (GR) activation has been shown to reduce adult hippocampal progenitor cell proliferation and neurogenesis. By contrast, mineralocorticoid receptor (MR) signaling is associated with neuronal survival in the dentate gyrus of the hippocampus, and impairment of hippocampal MR has...

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Foilsithe in:Front Endocrinol (Lausanne)
Main Authors: Gesmundo, Iacopo, Villanova, Tania, Gargantini, Eleonora, Arvat, Emanuela, Ghigo, Ezio, Granata, Riccarda
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2016
Ábhair:
Endocrinology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910464/
https://ncbi.nlm.nih.gov/pubmed/27379018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00066
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