Reconstitution of immune cell in liver and lymph node of adult- and newborn-engrafted humanized mice

BACKGROUND: Humanized mouse models are an increasingly popular preclinical model to study the human immune response in a biological system. There are a variety of protocols to generate these mice, each differing in the strain of the recipient, source of hematopoietic stem cells, and mode of transpla...

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Vydáno v:BMC Immunol
Hlavní autoři: Dykstra, Crystal, Lee, Amanda J., Lusty, Evan J., Shenouda, Mira M., Shafai, Mahsa, Vahedi, Fatemeh, Chew, Marianne V., Collins, Stephen, Ashkar, Ali A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910253/
https://ncbi.nlm.nih.gov/pubmed/27307066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-016-0157-9
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