Serum Gelatinases Levels in Multiple Sclerosis Patients during 21 Months of Natalizumab Therapy

Background. Natalizumab is a highly effective treatment approved for multiple sclerosis (MS). The opening of the blood-brain barrier mediated by matrix metalloproteinases (MMPs) is considered a crucial step in MS pathogenesis. Our goal was to verify the utility of serum levels of active MMP-2 and MM...

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Vydáno v:Dis Markers
Hlavní autoři: Castellazzi, Massimiliano, Bellini, Tiziana, Trentini, Alessandro, Delbue, Serena, Elia, Francesca, Gastaldi, Matteo, Franciotta, Diego, Bergamaschi, Roberto, Manfrinato, Maria Cristina, Volta, Carlo Alberto, Granieri, Enrico, Fainardi, Enrico
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909921/
https://ncbi.nlm.nih.gov/pubmed/27340316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8434209
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