Effect of Oral JZP-110 (ADX-N05) on Wakefulness and Sleepiness in Adults with Narcolepsy: A Phase 2b Study

STUDY OBJECTIVES: To evaluate the efficacy and safety of oral JZP-110, a second-generation wake-promoting agent with dopaminergic and noradrenergic activity, for treatment of impaired wakefulness and excessive sleepiness in adults with narcolepsy. METHODS: This was a phase 2b, randomized, double-bli...

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Detalhes bibliográficos
Publicado no:Sleep
Main Authors: Ruoff, Chad, Swick, Todd J., Doekel, Robert, Emsellem, Helene A., Feldman, Neil T., Rosenberg, Russell, Bream, Gary, Khayrallah, Moise A., Lu, Yuan, Black, Jed
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2016
Assuntos:
Neurological Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909620/
https://ncbi.nlm.nih.gov/pubmed/27166238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.5968
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