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Effect of DNase-I Treatment and Neutrophil Depletion on Acute Limb Ischemia Reperfusion Injury in Mice
OBJECTIVE: Extracellular traps-(ETs) consist of DNA-protein-complexes formed following tissue injury contributes to the inflammatory and thrombosis cascades thereby exacerbating injury. Exogenous DNase-1 has been suggested as a therapeutic strategy to limit injury in the brain and myocardium.. These...
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| Publicado no: | J Vasc Surg |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909598/ https://ncbi.nlm.nih.gov/pubmed/26704988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2015.01.031 |
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