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Brain GABA Detection in vivo with the J-editing (1)H MRS Technique: A Comprehensive Methodological Evaluation of Sensitivity Enhancement, Macromolecule Contamination and Test-Retest Reliability

Abnormalities in brain γ-aminobutyric acid (GABA) have been implicated in various neuropsychiatric and neurological disorders. However, in vivo GABA detection by proton magnetic resonance spectroscopy ((1)H MRS) presents significant challenges arising from low brain concentration, overlap by much st...

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Detalhes bibliográficos
Publicado no:NMR Biomed
Main Authors: Shungu, Dikoma C., Mao, Xiangling, Gonzales, Robyn, Soones, Tacara N., Dyke, Jonathan P., van der Veen, Jan Willem, Kegeles, Lawrence S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909570/
https://ncbi.nlm.nih.gov/pubmed/27173449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3539
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