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Esophageal Expression of Active IκB kinase-β in Mice Upregulates Tumor Necrosis Factor and Granulocyte Macrophage Colony-stimulating Factor, Promoting Inflammation and Angiogenesis

BACKGROUND & AIMS: IκB kinase-β (IKKβ) mediates activation of the nuclear factor-κB (NFκB), which regulates immune and inflammatory responses. Although NFκB is activated in cells from patients with inflammatory diseases or cancer, little is known about its roles in development and progression of...

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Publicado no:Gastroenterology
Main Authors: Tétreault, Marie-Pier, Weinblatt, Daniel, Ciolino, Jody Dyan, Klein-Szanto, Andres J, Sackey, Bridget K., Victor, Christina Twyman-Saint, Karakasheva, Tatiana, Teal, Valerie, Katz, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909513/
https://ncbi.nlm.nih.gov/pubmed/26896735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.02.025
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