Polycomb and lung cancer: When the dosage makes the (kind of) poison

The Polycomb transcriptional repressors regulate normal tissue homeostasis and their function is often hijacked during oncogenesis. We recently uncovered the Polycomb repressive complex-2 (PRC2) genes Ezh2 and Eed as oncogenotype-dependent cancer genes. Notably, within the same oncogenotype, PRC2 do...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Gargiulo, Gaetano, Citterio, Elisabetta, Serresi, Michela
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909420/
https://ncbi.nlm.nih.gov/pubmed/27314096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1152345
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