Differences in Enzymatic Properties Allow SodCI but Not SodCII To Contribute to Virulence in Salmonella enterica Serovar Typhimurium Strain 14028

Salmonella enterica serovar Typhimurium produces two Cu/Zn cofactored periplasmic superoxide dismutases, SodCI and SodCII. While mutations in sodCI attenuate virulence eightfold, loss of SodCII does not confer a virulence phenotype, nor does it enhance the defect observed in a sodCI background. Desp...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Krishnakumar, Radha, Craig, Maureen, Imlay, James A., Slauch, James M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2004
Sujets:
Molecular Biology of Pathogens
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC490929/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15292124/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.186.16.5230-5238.2004
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