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Metformin for Clozapine Associated Obesity: A Systematic Review and Meta-Analysis

BACKGROUND: Although clozapine is the gold-standard for treatment refractory schizophrenia, it has the worst metabolic profile of all antipsychotics. This is partly mediated by clozapine’s impact on glucagon-like peptide (GLP-1). There is an absence of robust evidence for effective treatments for cl...

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Veröffentlicht in:PLoS One
Hauptverfasser: Siskind, Dan J., Leung, Janni, Russell, Anthony W., Wysoczanski, Daniel, Kisely, Steve
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909277/
https://ncbi.nlm.nih.gov/pubmed/27304831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156208
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