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EGF Receptor Promotes Prostate Cancer Bone Metastasis by Downregulating miR-1 and Activating TWIST1

Dysregulation of the EGFR signaling axis enhances bone metastases in many solid cancers. However, the relevant downstream effector signals in this axis are unclear. miR-1 was recently shown to function as a tumor suppressor in prostate cancer cells, where its expression correlated with reduced metas...

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Detalhes bibliográficos
Publicado no:Cancer Res
Principais autores: Chang, Yung-Sheng, Chen, Wei-Yu, Yin, Juan Juan, Sheppard-Tillman, Heather, Huang, Jiaoti, Liu, Yen-Nien
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909124/
https://ncbi.nlm.nih.gov/pubmed/26071255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3380
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