Oncolytic herpes simplex virus kills stem-like tumor-initiating colon cancer cells

Stem-like tumor-initiating cells (TICs) are implicated in cancer progression and recurrence, and can be identified by sphere-formation and tumorigenicity assays. Oncolytic viruses infect, replicate in, and kill a variety of cancer cells. In this study, we seek proof of principle that TICs are suscep...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Warner, Susanne G, Haddad, Dana, Au, Joyce, Carson, Joshua S, O’Leary, Michael P, Lewis, Christina, Monette, Sebastien, Fong, Yuman
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909096/
https://ncbi.nlm.nih.gov/pubmed/27347556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.13
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