Ładuje się......
Novel protein–inhibitor interactions in site 3 of Ca(2+)-bound S100B as discovered by X-ray crystallography
Structure-based drug discovery is under way to identify and develop small-molecule S100B inhibitors (SBiXs). Such inhibitors have therapeutic potential for treating malignant melanoma, since high levels of S100B downregulate wild-type p53 tumor suppressor function in this cancer. Computational and X...
Zapisane w:
| Wydane w: | Acta Crystallogr D Struct Biol |
|---|---|
| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
International Union of Crystallography
2016
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4908867/ https://ncbi.nlm.nih.gov/pubmed/27303795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798316005532 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|