Cloning of the rat gene encoding choline acetyltransferase, a cholinergic neuron-specific marker.
The neurotransmitter acetylcholine is synthesized by choline acetyltransferase (ChAT; EC 2.3.1.6). Since the expression of ChAT in the nervous system is restricted to cholinergic neurons, it serves as a specific marker for these neurons. In Alzheimer disease, ChAT activity is markedly reduced in the...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1992
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49087/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1584771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.10.4387 |
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