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Caloric restriction improves diabetes-induced cognitive deficits by attenuating neurogranin-associated calcium signaling in high-fat diet-fed mice

Diabetes-induced cognitive decline has been recognized in human patients of type 2 diabetes mellitus and mouse model of obesity, but the underlying mechanisms or therapeutic targets are not clearly identified. We investigated the effect of caloric restriction on diabetes-induced memory deficits and...

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Bibliografske podrobnosti
izdano v:J Cereb Blood Flow Metab
Main Authors: Kim, Hwajin, Kang, Heeyoung, Heo, Rok Won, Jeon, Byeong Tak, Yi, Chin-ok, Shin, Hyun Joo, Kim, Jeonghyun, Jeong, Seon-Yong, Kwak, Woori, Kim, Won-Ho, Kang, Sang Soo, Roh, Gu Seob
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908619/
https://ncbi.nlm.nih.gov/pubmed/26661177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15606724
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