Longitudinal monitoring of immunoglobulin A glycosylation during pregnancy by simultaneous MALDI-FTICR-MS analysis of N- and O-glycopeptides

Immunoglobulin A (IgA) is a glycoprotein of which altered glycosylation has been associated with several pathologies. Conventional methods for IgA N- and O-glycosylation analysis are tedious, thus limiting such analyses to small sample sizes. Here we present a high-throughput strategy for the simult...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bondt, Albert, Nicolardi, Simone, Jansen, Bas C., Stavenhagen, Kathrin, Blank, Dennis, Kammeijer, Guinevere S. M., Kozak, Radoslaw P., Fernandes, Daryl L., Hensbergen, Paul J., Hazes, Johanna M. W., van der Burgt, Yuri E. M., Dolhain, Radboud J. E. M., Wuhrer, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908400/
https://ncbi.nlm.nih.gov/pubmed/27302155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27955
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