Longitudinal monitoring of immunoglobulin A glycosylation during pregnancy by simultaneous MALDI-FTICR-MS analysis of N- and O-glycopeptides

Immunoglobulin A (IgA) is a glycoprotein of which altered glycosylation has been associated with several pathologies. Conventional methods for IgA N- and O-glycosylation analysis are tedious, thus limiting such analyses to small sample sizes. Here we present a high-throughput strategy for the simult...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Bondt, Albert, Nicolardi, Simone, Jansen, Bas C., Stavenhagen, Kathrin, Blank, Dennis, Kammeijer, Guinevere S. M., Kozak, Radoslaw P., Fernandes, Daryl L., Hensbergen, Paul J., Hazes, Johanna M. W., van der Burgt, Yuri E. M., Dolhain, Radboud J. E. M., Wuhrer, Manfred
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908400/
https://ncbi.nlm.nih.gov/pubmed/27302155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27955
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