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Modulation of the Mesenchymal Stem Cell Secretome Using Computer-Controlled Bioreactors: Impact on Neuronal Cell Proliferation, Survival and Differentiation

In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/stromal cells (hMSCs) in the Central Nervous System (CNS) are mainly attributed to their secretome. The implementation of computer-controlled suspension bioreactors has shown to be a viable route for the expans...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Teixeira, Fábio G., Panchalingam, Krishna M., Assunção-Silva, Rita, Serra, Sofia C., Mendes-Pinheiro, Bárbara, Patrício, Patrícia, Jung, Sunghoon, Anjo, Sandra I., Manadas, Bruno, Pinto, Luísa, Sousa, Nuno, Behie, Leo A., Salgado, António J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908397/
https://ncbi.nlm.nih.gov/pubmed/27301770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27791
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