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A novel algorithm for calling mRNA m(6)A peaks by modeling biological variances in MeRIP-seq data

Motivation: N(6)-methyl-adenosine (m(6)A) is the most prevalent mRNA methylation but precise prediction of its mRNA location is important for understanding its function. A recent sequencing technology, known as Methylated RNA Immunoprecipitation Sequencing technology (MeRIP-seq), has been developed...

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Библиографические подробности
Опубликовано в: :Bioinformatics
Главные авторы: Cui, Xiaodong, Meng, Jia, Zhang, Shaowu, Chen, Yidong, Huang, Yufei
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908365/
https://ncbi.nlm.nih.gov/pubmed/27307641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw281
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