Delivery of dexamethasone from bioactive nanofiber matrices stimulates odontogenesis of human dental pulp cells through integrin/BMP/mTOR signaling pathways

Therapeutically relevant design of scaffolds is of special importance in the repair and regeneration of tissues including dentin and pulp. Here we exploit nanofiber matrices that incorporate bioactive glass nanoparticles (BGNs) and deliver the odontogenic drug dexamethasone (DEX) to stimulate the od...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Lim, Hyun-Chang, Nam, Ok Hyung, Kim, Mi-joo, El-Fiqi, Ahmed, Yun, Hyung-Mun, Lee, Yoo-Mi, Jin, Guang-Zhen, Lee, Hae-Hyoung, Kim, Hae-Won, Kim, Eun-Cheol
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2016
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907710/
https://ncbi.nlm.nih.gov/pubmed/27354790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S97846
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