Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells

Yersinia outer protein M (YopM) is a crucial immunosuppressive effector of the plaque agent Yersinia pestis and other pathogenic Yersinia species. YopM enters the nucleus of host cells but neither the mechanisms governing its nucleocytoplasmic shuttling nor its intranuclear activities are known. Her...

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Publicat a:PLoS Pathog
Autors principals: Berneking, Laura, Schnapp, Marie, Rumm, Andreas, Trasak, Claudia, Ruckdeschel, Klaus, Alawi, Malik, Grundhoff, Adam, Kikhney, Alexey G., Koch-Nolte, Friedrich, Buck, Friedrich, Perbandt, Markus, Betzel, Christian, Svergun, Dmitri I., Hentschke, Moritz, Aepfelbacher, Martin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907486/
https://ncbi.nlm.nih.gov/pubmed/27300509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005660
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