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Xtalk: a path-based approach for identifying crosstalk between signaling pathways

Motivation: Cells communicate with their environment via signal transduction pathways. On occasion, the activation of one pathway can produce an effect downstream of another pathway, a phenomenon known as crosstalk. Existing computational methods to discover such pathway pairs rely on simple overlap...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Tegge, Allison N., Sharp, Nicholas, Murali, T. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907392/
https://ncbi.nlm.nih.gov/pubmed/26400040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv549
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