Type I Interferon Counters or Promotes Coxiella burnetii Replication Dependent on Tissue

Coxiella burnetii is an intracellular pathogen and the cause of Q fever. Gamma interferon (IFN-γ) is critical for host protection from infection, but a role for type I IFN in C. burnetii infection has not been determined. Type I IFN supports host protection from a related pathogen, Legionella pneumo...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Hedges, Jodi F., Robison, Amanda, Kimmel, Emily, Christensen, Kelly, Lucas, Erin, Ramstead, Andrew, Jutila, Mark A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907146/
https://ncbi.nlm.nih.gov/pubmed/27068091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01540-15
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