Identification and Characterization of a Novel Aspergillus fumigatus Rhomboid Family Putative Protease, RbdA, Involved in Hypoxia Sensing and Virulence

Aspergillus fumigatus is the most common pathogenic mold infecting humans and a significant cause of morbidity and mortality in immunocompromised patients. In invasive pulmonary aspergillosis, A. fumigatus spores are inhaled into the lungs, undergoing germination and invasive hyphal growth. The fung...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Vaknin, Yakir, Hillmann, Falk, Iannitti, Rossana, Ben Baruch, Netali, Sandovsky-Losica, Hana, Shadkchan, Yona, Romani, Luigina, Brakhage, Axel, Kniemeyer, Olaf, Osherov, Nir
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907145/
https://ncbi.nlm.nih.gov/pubmed/27068092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00011-16
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