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The GLP-1 receptor agonists exendin-4 and liraglutide alleviate oxidative stress and cognitive and micturition deficits induced by middle cerebral artery occlusion in diabetic mice

BACKGROUND: Glucagon-like peptide 1 (GLP-1) analogs protect a variety of cell types against oxidative damage and vascular and neuronal injury via binding to GLP-1 receptors. This study aimed to investigate the effects of the GLP-1 analogs exendin-4 and liraglutide on cerebral blood flow, reactive ox...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Li, Ping-Chia, Liu, Li-Fen, Jou, Ming-Jia, Wang, Hao-Kuang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4907076/
https://ncbi.nlm.nih.gov/pubmed/27296974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-016-0272-9
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