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Eosinophils enhance WNT-5a and TGF-β(1) genes expression in airway smooth muscle cells and promote their proliferation by increased extracellular matrix proteins production in asthma
BACKGROUND: Recent studies have suggested that eosinophils may have a direct effect on airway smooth muscle cells (ASMC), causing their proliferation in patients with asthma, but the precise mechanism of the interaction between these cells remains unknown. We propose that changes in Wnt signaling ac...
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| Publié dans: | BMC Pulm Med |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906992/ https://ncbi.nlm.nih.gov/pubmed/27297409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-016-0254-9 |
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