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Targeting the ataxia telangiectasia mutated pathway for effective therapy against hirsutine-resistant breast cancer cells

The present authors have recently demonstrated that hirsutine, one of the major alkaloids in Uncaria species, promotes cell apoptosis by inducing DNA damage and suppresses metastasis of breast cancer cells. Despite its potent anti-cancer activity, certain types of human breast cancer cells exhibit r...

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Podrobná bibliografie
Vydáno v:Oncol Lett
Hlavní autoři: LOU, CHENGHUA, YOKOYAMA, SATORU, ABDELHAMED, SHERIF, SAIKI, IKUO, HAYAKAWA, YOSHIHIRO
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906959/
https://ncbi.nlm.nih.gov/pubmed/27347141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4554
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