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Minimal impact of age and housing temperature on the metabolic phenotype of Acc2(−/−) mice

An important regulator of fatty acid oxidation (FAO) is the allosteric inhibition of CPT-1 by malonyl-CoA produced by the enzyme acetyl-CoA carboxylase 2 (ACC2). Initial studies suggested that deletion of Acc2 (Acacb) increased fat oxidation and reduced adipose tissue mass but in an independently ge...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Brandon, Amanda E, Stuart, Ella, Leslie, Simon J, Hoehn, Kyle L, James, David E, Kraegen, Edward W, Turner, Nigel, Cooney, Gregory J
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906541/
https://ncbi.nlm.nih.gov/pubmed/26668208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-15-0444
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