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(177)Lu-OPS201 targeting somatostatin receptors: in vivo biodistribution and dosimetry in a pig model

BACKGROUND: (177)Lu is used in peptide receptor radionuclide therapies for the treatment of neuroendocrine tumors. Based on the recent literature, SST2 antagonists are superior to agonists in tumor uptake. The compound OPS201 is the novel somatostatin antagonist showing the highest SST2 affinity. Th...

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Detalles Bibliográficos
Publicado en:EJNMMI Res
Main Authors: Beykan, Seval, Dam, Jan S., Eberlein, Uta, Kaufmann, Jens, Kjærgaard, Benedict, Jødal, Lars, Bouterfa, Hakim, Bejot, Romain, Lassmann, Michael, Jensen, Svend Borup
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906090/
https://ncbi.nlm.nih.gov/pubmed/27294582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-016-0204-9
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