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Multitarget Multiscale Simulation for Pharmacological Treatment of Dystonia in Motor Cortex

A large number of physiomic pathologies can produce hyperexcitability in cortex. Depending on severity, cortical hyperexcitability may manifest clinically as a hyperkinetic movement disorder or as epilpesy. We focus here on dystonia, a movement disorder that produces involuntary muscle contractions...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Neymotin, Samuel A., Dura-Bernal, Salvador, Lakatos, Peter, Sanger, Terence D., Lytton, William W.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906029/
https://ncbi.nlm.nih.gov/pubmed/27378922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00157
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