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Ubiquitination independent of E1 and E2 enzymes by bacterial effectors

Signaling by ubiquitination regulates virtually every cellular process in eukaryotes. Covalent attachment of ubiquitin to a substrate is catalyzed by the E1, E2 and E3 three-enzyme cascade (1), which links the C terminus of ubiquitin via an isopeptide bond mostly to the ε-amino group of a lysine of...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Qiu, Jiazhang, Sheedlo, Michael J., Yu, Kaiwen, Tan, Yunhao, Nakayasu, Ernesto S., Das, Chittaranjan, Liu, Xiaoyun, Luo, Zhao-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905768/
https://ncbi.nlm.nih.gov/pubmed/27049943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17657
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