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Pasteurella multocida toxin is a potent inducer of anchorage-independent cell growth.

The growth of many normal cells requires contact with an adhesive substratum, a requirement that is frequently abrogated in the transformed phenotype. We have explored pathways that can lead to the anchorage-independent growth of cultured Rat-1 fibroblasts. Pasteurella multocida toxin (PMT), a 146-k...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Higgins, T E, Murphy, A C, Staddon, J M, Lax, A J, Rozengurt, E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49057/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1584759/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.10.4240
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