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Natural Phenolic Inhibitors of Trichothecene Biosynthesis by the Wheat Fungal Pathogen Fusarium culmorum: A Computational Insight into the Structure-Activity Relationship

A model of the trichodiene synthase (TRI5) of the wheat fungal pathogen and type-B trichothecene producer Fusarium culmorum was developed based on homology modelling with the crystallized protein of F. sporotrichioides. Eight phenolic molecules, namely ferulic acid 1, apocynin 2, propyl gallate 3, e...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Pani, Giovanna, Dessì, Alessandro, Dallocchio, Roberto, Scherm, Barbara, Azara, Emanuela, Delogu, Giovanna, Migheli, Quirico
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905666/
https://ncbi.nlm.nih.gov/pubmed/27294666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157316
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