Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of “towards analysis” in chronic lymphocytic leukaemia

BACKGROUND: Somatic Hypermutation (SHM) refers to the introduction of mutations within rearranged V(D)J genes, a process that increases the diversity of Immunoglobulins (IGs). The analysis of SHM has offered critical insight into the physiology and pathology of B cells, leading to strong prognostica...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Kavakiotis, Ioannis, Xochelli, Aliki, Agathangelidis, Andreas, Tsoumakas, Grigorios, Maglaveras, Nicos, Stamatopoulos, Kostas, Hadzidimitriou, Anastasia, Vlahavas, Ioannis, Chouvarda, Ioanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905615/
https://ncbi.nlm.nih.gov/pubmed/27295298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1044-3
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