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Tissue-inappropriate derepression of FOXC1 is frequent and functional in human acute myeloid leukemia

Tissue-inappropriate derepression of the mesenchymal transcription factor gene Forkhead Box C1 (FOXC1) occurs in approximately 20% of patients with acute myeloid leukemia. Through experimental and bioinformatics analyses, we have demonstrated this to be both functional (enhancing the myeloid lineage...

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Bibliographic Details
Published in:Mol Cell Oncol
Main Authors: Somerville, Tim D. D., Somervaille, Tim C. P.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905553/
https://ncbi.nlm.nih.gov/pubmed/27308636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1131355
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