A strategy to eradicate well-developed Krebs-2 ascites in mice

We describe the strategy, which allows curing experimental mice engrafted with Krebs-2 ascites. The strategy is based on the facts that i) Krebs-2 tumor-initiating stem cells (TISCs) are naturally capable of internalizing fragments of extracellular double-stranded DNA (dsDNA); ii) upon delivery into...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Potter, Ekaterina A., Dolgova, Evgenia V., Proskurina, Anastasia S., Minkevich, Alexandra M., Efremov, Yaroslav R., Taranov, Oleg S., Omigov, Vladimir V., Nikolin, Valeriy P., Popova, Nelly A., Bayborodin, Sergey I., Ostanin, Alexander A., Chernykh, Elena R., Kolchanov, Nikolay A., Shurdov, Mikhail A., Bogachev, Sergey S.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905495/
https://ncbi.nlm.nih.gov/pubmed/26872383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7311
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