Mucin glycosylating enzyme GALNT2 suppresses malignancy in gastric adenocarcinoma by reducing MET phosphorylation

Glycosylation affects malignancy in cancer. Here, we report that N- acetylgalactosaminyltransferase 2 (GALNT2), an enzyme that mediates the initial step of mucin type-O glycosylation, suppresses malignant phenotypes in gastric adenocarcinoma (GCA) by modifying MET (Hepatocyte growth factor receptor)...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Shin-Yun, Shun, Chia-Tung, Hung, Kuan-Yu, Juan, Hsueh-Fen, Hsu, Chia-Lang, Huang, Min-Chuan, Lai, I-Rue
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905470/
https://ncbi.nlm.nih.gov/pubmed/26848976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7081
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