EZH2 promotes cell migration and invasion but not alters cell proliferation by suppressing E-cadherin, partly through association with MALAT-1 in pancreatic cancer

Enhancer of zeste homolog 2 (EZH2) is an essential component of the polycomb repressive complex 2 (PRC2), which is required for epigenetic silencing of target genes, including those affecting cancer progression. Its role in pancreatic cancer remains to be clarified; therefore, we investigated the ef...

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Vydáno v:Oncotarget
Hlavní autoři: Han, Ting, Jiao, Feng, Hu, Hai, Yuan, Cuncun, Wang, Lei, Jin, Zi-Liang, Song, Wei-feng, Wang, Li-Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905466/
https://ncbi.nlm.nih.gov/pubmed/26848980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7156
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