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Compensatory roles of CD8(+) T cells and plasmacytoid dendritic cells in gut immune regulation for reduced function of CD4(+) Tregs

CD4(+) Tregs need to migrate from the mucosal periphery into the draining lymph node via CCR7 to exert their suppressive effects. In this study, we investigated whether CCR7 deficiency resulted in failure of immune suppression in 2% dextran sulfate sodium-induced colitis. Unexpectedly, intestinal in...

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書目詳細資料
發表在:Oncotarget
Main Authors: Kim, Young-In, Lee, Bo-Ra, Cheon, Jae-Hee, Kwon, Bo-Eun, Kweon, Mi-Na, Ko, Hyun-Jeong, Chang, Sun-Young
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905450/
https://ncbi.nlm.nih.gov/pubmed/26908454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7510
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