First in-depth analysis of the novel Th2-type cytokines in salmonid fish reveals distinct patterns of expression and modulation but overlapping bioactivities

IL-4 and IL-13 are closely related canonical type-2 cytokines in mammals and have overlapping bioactivities via shared receptors. They are frequently activated together as part of the same immune response and are the signature cytokines produced by T-helper (Th)2 cells and type-2 innate lymphoid cel...

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Pubblicato in:Oncotarget
Autori principali: Wang, Tiehui, Johansson, Petronella, Abós, Beatriz, Holt, Amy, Tafalla, Carolina, Jiang, Youshen, Wang, Alex, Xu, Qiaoqing, Qi, Zhitao, Huang, Wenshu, Costa, Maria M., Diaz-Rosales, Patricia, Holland, Jason W., Secombes, Christopher J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper: Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905449/
https://ncbi.nlm.nih.gov/pubmed/26870894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7295
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