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Targeting c-fms kinase attenuates chronic aristolochic acid nephropathy in mice

Aristolochic acid nephropathy (AAN) is a progressive kidney disease caused by some Chinese herbal medicines, but treatment remains ineffective. Macrophage accumulation is an early feature in human and experimental AAN; however, the role of macrophages in chronic AAN is unknown. We report here that t...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Dai, Xiao Y., Huang, Xiao R., Zhou, Li, Zhang, Lin, Fu, Ping, Manthey, Carl, Nikolic-Paterson, David J., Lan, Hui Y.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905443/
https://ncbi.nlm.nih.gov/pubmed/26909597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7460
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